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CLUSTAL W Multiple Sequence Alignment Program
ClustalW was written by Des Higgins (now at University College, Cork,
Ireland) (des@chah.ucc.ie), Julie Thompson (julie@IGBMC.u-strasbg.fr),
Toby Gibson, (Gibson@EMBL-Heidelberg.DE), and Franc'ois Jeanmougin
(pingouin@igbmc.u-strasbg.fr). It is a complete rewrite and upgrade of
the Clustal and ClustalV packages. which were developed by Des
Higgins. New features include the ability to detect read different
input formats (NBRF/PIR, Fasta, EMBL/Swissprot); align old alignments;
produce phylogenetic trees after alignment (Neighbor Joining trees
with a bootstrap option); write different alignment formats (Clustal,
NBRF/PIR, GCG, PHYLIP); full command line interface. It is described
in the following papers:
Thompson, J.D., D. G. Higgins and T. J. Gibson. 1994. CLUSTAL W:
improving the sensitivity of progressive multiple sequence alignment
through sequence weighting, positions-specific gap penalties and
weight matrix choice. Nucleic Acids Research 22: 4673-4680.
Higgins, D. G., J. D. Thompson, and T. J. Gibson. 1996. Using
CLUSTAL for multiple sequence alignments. Methods in Enzymology 266:
383-402.
WWW: http://www-igbmc.u-strasbg.fr/BioInfo/ClustalX/Top.html
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