================================================================================ Also remember to add to your Apache configuration in the appropriate context: PythonPath "['/path/to/foo', '/path/to/bar']" AddHandler python-program .py PythonHandler foobar PythonDebug On For more information, see http://www.modpython.org/. And, if you built apache without thread support, you may need to add the following lines to $PREFIX/sbin/envvars: LD_PRELOAD=/usr/lib/libc_r.so export LD_PRELOAD ================================================================================